KINtaro Database
FAMILY: RIO1 (PKLF000036)
Description
The founding member of the RIO family of atypical serine kinases, is universally present in all organisms from archaea to eukaryotes. Its activity has been demonstrated to be essential in Saccharomyces cerevisiae for various cellular processes, including the processing of 16S/18S ribosomal RNA, proper cell cycle progression, metabolism, chromosome maintenance and cancerogenesis [PMID: 30515528].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues: based on - collapsed family logo, 3D structure model, PDB (4OTP) FATCAT structural pairwise alignment with 4OTP, 1ATP, 1O6Y and 6PWD
Structure
PKL domain
HMM Model
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Sequences
Aligned domain sequences
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Unaligned domain sequences
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Full sequences
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Description
The founding member of the RIO family of atypical serine kinases, is universally present in all organisms from archaea to eukaryotes. Its activity has been demonstrated to be essential in Saccharomyces cerevisiae for various cellular processes, including the processing of 16S/18S ribosomal RNA, proper cell cycle progression, metabolism, chromosome maintenance and cancerogenesis [PMID: 30515528].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues: based on - collapsed family logo, 3D structure model, PDB (4OTP) FATCAT structural pairwise alignment with 4OTP, 1ATP, 1O6Y and 6PWD
Structure
PKL domain
HMM Model
WebLogo
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