KINtaro Database
FAMILY: IucA_IucC (PKLF000022)
Description
The IucA/IucC PKL family is involved in the biosynthesis of the siderophore aerobactin. Siderophores are small molecules produced by microorganisms to scavenge and acquire iron, an essential nutrient for their growth and survival. Aerobactin is a specific siderophore produced by some pathogenic bacteria [PMID: 3087960].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues: K72 E91, D166, D184 changed, N-lobe YukC presents an additional α-helix in the ATP-binding pocket and is unable to bind ATP, PMID: 36154281;
Structure
PKL domain
HMM Model
WebLogo
×
![]()
Sequences
Aligned domain sequences
Download sequence
Unaligned domain sequences
Download sequence
Full sequences
Download sequence
Description
The IucA/IucC PKL family is involved in the biosynthesis of the siderophore aerobactin. Siderophores are small molecules produced by microorganisms to scavenge and acquire iron, an essential nutrient for their growth and survival. Aerobactin is a specific siderophore produced by some pathogenic bacteria [PMID: 3087960].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues: K72 E91, D166, D184 changed, N-lobe YukC presents an additional α-helix in the ATP-binding pocket and is unable to bind ATP, PMID: 36154281;
Structure
PKL domain
HMM Model
WebLogo
×
![]()