KINtaro Database
FAMILY: IPK (PKLF000021)
Description
Inositol polyphosphate kinase family (IPK) plays significant roles in vacuole biogenesis and the cell's response to specific environmental stresses. These kinases are responsible for the production of soluble inositol phosphates, and their kinase activity is essential for this function [PMID: 12828642].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues: conserved GSSLL motif (equivalent to the catalytic loop in PKA) is required for enzymatic activity, based on - 3D structure model, PDB (6CN7), FATCAT structural pairwise alignment with 6CN7, 1ATP and 1O6Y, PMID: 15350214
Structure
PKL domain
HMM Model
WebLogo
×
![]()
Sequences
Aligned domain sequences
Download sequence
Unaligned domain sequences
Download sequence
Full sequences
Download sequence
Description
Inositol polyphosphate kinase family (IPK) plays significant roles in vacuole biogenesis and the cell's response to specific environmental stresses. These kinases are responsible for the production of soluble inositol phosphates, and their kinase activity is essential for this function [PMID: 12828642].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues: conserved GSSLL motif (equivalent to the catalytic loop in PKA) is required for enzymatic activity, based on - 3D structure model, PDB (6CN7), FATCAT structural pairwise alignment with 6CN7, 1ATP and 1O6Y, PMID: 15350214
Structure
PKL domain
HMM Model
WebLogo
×
![]()