KINtaro Database
FAMILY: Ins_P5_2-kin (PKLF000020)
Description
Inositol-pentakisphosphate 2-kinase is an enzyme family that catalyzes the phosphorylation of inositol-pentakisphosphate to form inositol hexakisphosphate (InsP6). InsP6 plays important roles in various cellular processes including mRNA export, endocytosis, ion channel regulation, and nonhomologous end-joining [PMID: 10960485].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues: unusual conserved motifs: M1-4, based on - PDB(2XAL), PMID: 20453199, family collapsed logo, 3D structure model, HHpred, FATCAT structural pairwise alignment with 2XAL
Structure
PKL domain
HMM Model
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Sequences
Aligned domain sequences
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Unaligned domain sequences
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Full sequences
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Description
Inositol-pentakisphosphate 2-kinase is an enzyme family that catalyzes the phosphorylation of inositol-pentakisphosphate to form inositol hexakisphosphate (InsP6). InsP6 plays important roles in various cellular processes including mRNA export, endocytosis, ion channel regulation, and nonhomologous end-joining [PMID: 10960485].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues: unusual conserved motifs: M1-4, based on - PDB(2XAL), PMID: 20453199, family collapsed logo, 3D structure model, HHpred, FATCAT structural pairwise alignment with 2XAL
Structure
PKL domain
HMM Model
WebLogo
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![]()