KINtaro Database
FAMILY: EcKL (PKLF000013)
Description
The ecdysteroid kinase-like family is a group of enzymes responsible for the phosphorylation of ecdysteroids, which are insect growth and molting hormones, at the C-22 position, leading to the formation of physiologically inactive ecdysteroid 22-phosphates. Only ecdysteroid 22-kinase from Bombyx mori, has characterised substrates, including 2-deoxyecdysone, ecdysone, and 20-hydroxyecdysone [PMID: 16899460].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues (predicted only): based on - collapsed family logo, 3D structure model, HHpred, FATCAT structural pairwise alignment with 1ATP, 6PWD and 1O6Y, PMID: 16899460
HMM Model
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Sequences
Aligned domain sequences
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Unaligned domain sequences
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Full sequences
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Description
The ecdysteroid kinase-like family is a group of enzymes responsible for the phosphorylation of ecdysteroids, which are insect growth and molting hormones, at the C-22 position, leading to the formation of physiologically inactive ecdysteroid 22-phosphates. Only ecdysteroid 22-kinase from Bombyx mori, has characterised substrates, including 2-deoxyecdysone, ecdysone, and 20-hydroxyecdysone [PMID: 16899460].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues (predicted only): based on - collapsed family logo, 3D structure model, HHpred, FATCAT structural pairwise alignment with 1ATP, 6PWD and 1O6Y, PMID: 16899460
HMM Model
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