KINtaro Database
FAMILY: CotH (PKLF000008)
Description
The CotH kinase domain is a member of the atypical protein kinase family, which phosphorylates CotB and CotG, proteins that play a crucial role in the assembly of the spore coat of Bacillus subtilis [PMID: 27185916].
Origin
phmmer: 0.0001;
database: nr;
sequence_cutoff: 100aa;
clustering: cdhit: 90%;
catalytic residues: salt bridge K72-E91 replaced by hydrogen bond between R50-N81 based on - collapsed family logo, 3D structure model, PDB (5JD9), FATCAT structural pairwise alignment with 5JD9, 1ATP, PMID: 25498144
Structure
PKL domain
HMM Model
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Sequences
Aligned domain sequences
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Unaligned domain sequences
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Full sequences
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Description
The CotH kinase domain is a member of the atypical protein kinase family, which phosphorylates CotB and CotG, proteins that play a crucial role in the assembly of the spore coat of Bacillus subtilis [PMID: 27185916].
Origin
phmmer: 0.0001; database: nr; sequence_cutoff: 100aa; clustering: cdhit: 90%; catalytic residues: salt bridge K72-E91 replaced by hydrogen bond between R50-N81 based on - collapsed family logo, 3D structure model, PDB (5JD9), FATCAT structural pairwise alignment with 5JD9, 1ATP, PMID: 25498144
Structure
PKL domain
HMM Model
WebLogo
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