ART Database

An ART family found in bacteria and eukaryotes. It has a very poorly conserved active site - the only well conserved residue is an aromatic residue located on strand 5 (this corresponds to a hydrophobic residue from the HHh clade).

These enzymes correspond to Agrobacterium rolC and were characterised along with rolB. RolB and rolC were originally classified as glycoside hydrolase family 40 and 41 respectively. RolB has subsequently been shown [PUBMED:8596628] to have tyrosine phosphatase activity.

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Source: Pfam 34.0, rp75 Number of sequences: 53 Average length of the domain: 164 aa HMM: Model length: 200 Clustering level: 80% Alignment: ClustalO Additional information: sequences longer than 50 amino acids