ART Database

Bacterial family of ADP-ribosyltransferases, appears to be specific to Rhodospirillum, Rhodobacter and Azospirillum.

This family consists of several bacterial dinitrogenase reductase ADP-ribosyltransferase (DRAT) proteins. Members of this family seem to be specific to Rhodospirillum, Rhodobacter and Azospirillum species. Dinitrogenase reductase ADP-ribosyl transferase (DRAT) carries out the transfer of the ADP-ribose from NAD to the Arg-101 residue of one subunit of the dinitrogenase reductase homodimer, resulting in inactivation of that enzyme. Dinitrogenase reductase-activating glycohydrolase (DRAG) removes the ADP-ribose group attached to dinitrogenase reductase, thus restoring nitrogenase activity. The DRAT-DRAG system negatively regulates nitrogenase activity in response to exogenous NH4+ or energy limitation in the form of a shift to darkness or to anaerobic conditions [PUBMED:11160092].

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Source: Pfam 34.0, rp75 Number of sequences: 181 Average length of the domain: 252 aa HMM: Model length: 253 Clustering level: 80% Alignment: ClustalO Additional information: sequences longer than 50 amino acids